Dominant inhibitory receptors for HLA class I (HLA-I) endow NK cells with high intrinsic responsiveness. a process termed licensing or education. but hinder their ability to kill HLA-I+ tumor cells. Cancer immunotherapy with adoptive transfer of NK cells must overcome inhibitory signals by such receptors to promote elimination of HLA-I+ tumor cells. https://parisnaturalfoodes.shop/product-category/mag-smart-lemon/